EFFECTIVITY OF DIFFERENT SODIUM AND ULTRAFILTRATION PROFILES ON HEMODIALYSIS-INDUCED HYPOTENSION

Dialysate sodium (Nα) and ultrafitration (UF) profiling are two methods to reduce dialysis-induced hypotension. The aim of this study was to determine the efficacy of combining these techniques to reduce dialysisinduced hypotension in chronic hemodialysis (HD) patients.

In our hemodialysis center there were 69 patients. Initially standard dialysis with constant dialysate sodium and ultrafiltration protocol were used in all patients. In nineteen patients (27%) dialysis-induced hypotension was established.Their ages were 48.53±16.92 years. (14 female and 5 male). Their dialysis duration were 36.00±40.45 months.In these patients; six different sodium and ultrafiltration profiling were used to prevent dialysisinduced hypotension.

In ten (52.6%) patients sodium and ultrafiltration profiling (I) were used and dialysis-induced hypotension was prevented. In five (15.7%) patients sodium and ultrafiltration profiling (V) were used and dialysis-induced hypotension was prevented. In two (10.4%) patients sodium and ultrafiltration profiling (IV)7 were used and dialysis-induced hypotension was prevented. In one (5.2%) patient sodium and ultrafitration profiling (111) were used and dialysis induced hypotension was prevented. In three (15.7%) patients different sodium and ultrafitration profiles were used, but dialysis-induced hypotension could not be prevented

In conclusion, we demonstrated that combined dialysate sodium concentration and ultrafitration profiling significantly reduce dialysis-induced hypotension comparing to standard dialysis with constant dialysate sodium and ultrafiltration. We recommend that Nα and UF profiles should be used routinely in hemodialysis practice.