Articles

EFFECTS OF HEMODIALYSIS ON PROTEIN CARBONYL CONTENT AND SULPHYDRYL GROUP LEVELS

Volume 10 · Issue 2 Publish Date: March 15, 2019
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Tülay KÖKEN
Afyon Kocatepe Üniversitesi Tıp Fakültesi Biyokimya Anabilim Dalı, AFYON
Ahmet KAHRAMAN
Afyon Kocatepe Üniversitesi Tıp Fakültesi Biyokimya Anabilim Dalı, AFYON
Mustafa SERTESER
Afyon Kocatepe Üniversitesi Tıp Fakültesi Biyokimya Anabilim Dalı, AFYON
Güldane ÇETİNKAYA
Afyon Özel Diyaliz Merkezi, AFYON
KÖKEN, T., KAHRAMAN, A., SERTESER, M., & ÇETİNKAYA, G. (2019). EFFECTS OF HEMODIALYSIS ON PROTEIN CARBONYL CONTENT AND SULPHYDRYL GROUP LEVELS. Turkish Journal of Nephrology, 10(2), 83–85. Retrieved from https://www.turkjnephrol.org/index.php/pub/article/view/255
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Abstract

We have assessed the effect of a single episode of hemodialysis on protein carbonyl content and protein sulfydryl (SH) groups in 28 patients and 14 control subjects.

In chronic renal failure (CRF) patients the carbonyl content increased when compaired to the controls (p<0.001). But there were no statistically significant changes found between pre-hemodialysis and post-hemodialysis. The protein SH groups decreased significantly in CRF patients (p<0.001). After hemodialysis the protein SH groups increased significantly (p<0.001).

Base on these findings, it can be concluded that hemodialysis does not lead to any loss in protein carbonyl content but increases the protein SH groups.

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Article Info
Published In
Journal Turkish Journal of Nephrology
Volume / Issue Volume 10 · Issue 2
Pages 83-85
History
Published Online March 15, 2019
Copyright
Affiliations
Tülay KÖKEN
Afyon Kocatepe Üniversitesi Tıp Fakültesi Biyokimya Anabilim Dalı, AFYON
Ahmet KAHRAMAN
Afyon Kocatepe Üniversitesi Tıp Fakültesi Biyokimya Anabilim Dalı, AFYON
Mustafa SERTESER
Afyon Kocatepe Üniversitesi Tıp Fakültesi Biyokimya Anabilim Dalı, AFYON
Güldane ÇETİNKAYA
Afyon Özel Diyaliz Merkezi, AFYON
Cite this Article
KÖKEN, T., KAHRAMAN, A., SERTESER, M., & ÇETİNKAYA, G. (2019). EFFECTS OF HEMODIALYSIS ON PROTEIN CARBONYL CONTENT AND SULPHYDRYL GROUP LEVELS. Turkish Journal of Nephrology, 10(2), 83–85. Retrieved from https://www.turkjnephrol.org/index.php/pub/article/view/255
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