1.25 (OH)2 CHOLECALCIFEROL PULSE THERAPY AND THE EFFECTS OF DIFFERENT DIALYSIS MEMBRANES ON SERUM PTH LEVELS OF HEMODIALYSIS PATIENTS

30 patients, 10 female, 20 male has been included in this study. In 15 cases high-flux polysulfon and in 15 patients cuprophan membranes are used. Cα ion level of dialisate was 1.5 mmollL for both groups. Following one month of therapy with 0.07 mglkg and six months of therapy with 0.03 mglkg, three times a week, PTH, Alkaline Phosphatase and ionized Cα levels were significantly normal. CaCO^ was used with the dose of 3 gr/day as a phosphate binding agent. As a result, we believe for the treatment of secondary hyperparathyroidism the intermittent oral calcitriol pulse therapy depending on body weight, low dialisate calcium and using biocompatible membranes due to their high permeability and high PTH clearance are very effective, safe and a better choice.