EISSN 2667-4440

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Turkish Journal of Nephrology

33 437 2024

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Review

The Frailty of Advanced Kidney Disease: The Role of Mitochondria

Abdulmecit Yıldız ¹ , Talat Alp Ikizler ^{2 3}

Author Affiliation(s)

1.

Division of Nephrology, Uludağ University, Faculty of Medicine Bursa, Türkiye

2.

Division of Nephrology and Hypertension, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA

3.

Veterans Health Affairs, Tennessee Valley Healthcare System, Nashville, TN, USA

Turkish J Nephrol 2022; 31: 190-193

DOI: 10.5152/turkjnephrol.2022.22317

Keywords : Chronic kidney disease, mitochondria, muscles

Read: 1095 Downloads: 520 Published: 01 July 2022

Volume 31, Issue 3, July 2022

Previous Article

Uremic toxins contribute to the impairment of mitochondrial function that subsequently could result in organ failure. Mitochondrial dysfunction also plays an essential role in the pathogenesis of sarcopenia in chronic kidney disease patients. It may be feasible to assess the effect of mitoc hondr ial-t arget ed drugs to treat sarcopenia in patients with chronic kidney disease.

Cite this article as: Yıldız A, İkizler TA. The frailty of advanced kidney disease: The role of mitochondria. Turk J Nephrol. 2022;31(3):190-193.

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